---
name: "evol"
section: "1"
platform: "linux"
package: "python3-prody"
version: "2.3.1+dfsg-3+deb12u2"
release: "Debian 12 (Bookworm)"
platforms: ["linux"]
url: "https://new.carta.tech/evol"
---

# evol(1)

Sequence Evolution and Dynamics Analysis

## NAME

ProDy - Sequence Evolution and Dynamics Analysis

## DESCRIPTION

usage: evol \[-h\] \[-c\] \[-v\] \[-e\]

-

  {search,fetch,filter,refine,merge,occupancy,conserv,coevol,rankorder} ...

Evol: Sequence Evolution and Dynamics Analysis

### options:

- **-h**, **--help**

  show this help message and exit

- **-c**, **--cite**

  print citation info and exit

- **-v**, **--version**

  print ProDy version and exit

- **-e**, **--examples**

  show usage examples and exit

### subcommands:

-

  {search,fetch,filter,refine,merge,occupancy,conserv,coevol,rankorder}

- search

  search Pfam with given query

- fetch

  fetch MSA files from Pfam

- filter

  filter an MSA using sequence labels

- refine

  refine an MSA by removing gapped rows/colums

- merge

  merge multiple MSAs based on common labels

- occupancy

  calculate occupancy of rows and columns in MSA

- conserv

  analyze conservation using Shannon entropy

- coevol

  analyze co-evolution using mutual information

- rankorder

  identify highly coevolving pairs of residues

See 'evol \<command\> **-h**' for more information on a specific command.